When chemotherapy may be recommended before breast cancer surgery and how response can guide a personalised surgical plan.
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Neoadjuvant chemotherapy is treatment given before surgery. It may shrink a breast tumour, make breast-conserving surgery possible, treat microscopic disease early and show how the cancer responds to medication.
It is most useful for particular tumour subtypes and stages and is not automatically needed for every breast cancer. The sequence of treatment should be agreed after imaging, biopsy and multidisciplinary review.
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